Clinical Trials in Head Injury

Clinical trials in head injury.

Traumatic brain injury (TBI) remains a major public health problem globally. In the United States the incidence of closed head injuries admitted to hospitals is conservatively estimated to be 200 per 100,000 population, and the incidence of penetrating head injury is estimated to be 12 per 100,000, the highest of any developed country in the world. This yields an approximate number of 500,000 n...

Quality of randomised controlled trials in head injury. Trials in head injury are more complex than review suggests.

Epidemiology of head injury in Kerman

This cross-sectional study was carried out during the year 1990 at Shahid Bahonar hospital of Kerman. During this period 1350 patients were admitted, 53℅ of whom were below the age cases occurring between 3 to 7 pm. The highest rate of admission was in summer. The average stay at the hospital was 7.2 days and the mortality rate in these patients was 8.14℅ , twenty four of whom (22.2℅) expired a...

Evaluation of Clinical Trials

In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...

Evidence Based Medicine: Clinical Trials

Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...